Host factors influencing the activation of tuberculosis in HIV positive individuals with latent TB infection
نویسندگان
چکیده
Background TB kills 1.3 million persons annually, including 275,000 people in India. An estimated 40% of the population in India has LTBI (Latent Tuberculosis Infection), a significant percentage of them being infected with HIV. HIV infection increases the likelihood of LTBI progressing to active TB. Vaccination and immunotherapeutic strategies are alternative approaches that contribute greatly to TB control in HIV+ persons with LTBI.
منابع مشابه
تست پوستی توبرکولین: مقاله مروری
Historically, tuberculosis has been the leading cause of death throughout human history. Tuberculosis infection (TB) causes by Mycobacterium tuberculosis that is very dangerous and can affect any parts of the body, especially lungs. Tuberculosis infection still remains a serious threat to human public health due to its contagious nature, capability to stay latent form in host for indefinite tim...
متن کاملLatent Tuberculosis in HIV positive, diagnosed by the M. Tuberculosis Specific Interferon-γ test
BACKGROUND Although tuberculosis (TB) is a minor problem in Denmark, severe and complicated cases occur in HIV positive. Since the new M. tuberculosis specific test for latent TB, the QuantiFERON-TB In-Tube test (QFT-IT) became available the patients in our clinic have been screened for the presence of latent TB using the QFT-IT test. We here report the results from the first patients screened....
متن کاملThe Prevalence of Latent Tuberculosis Infection and Smear Positive Pulmonary Tuberculosis in People with Household Close Contact with Tuberculosis in North of Iran
One of the recommended strategies for preventing tuberculosis is to screen high-risk populations with respect to Mycobacterium tuberculosis (TB) infection. The aim of the present study was to investigate latent infection and active tuberculosis in people with close household contact. It was a cross-sectional descriptive, analytical study with the sample size of 668 people from homes with one in...
متن کاملManagement of Latent Tuberculosis in Iran
Although screening, finding and treatment of active cases of tuberculosis is very important for control of disease in the community, for reaching to the goals planed by world health organization and approaching to elimination of the disease, it is necessary to find and treat persons with latent infection. Concerning to high prevalence of latent TB in developing countries and resource limitation...
متن کاملLatent tuberculosis infection: what we know about its genetic control?
About 90% of all cases of tuberculosis (TB) infection are comprised of latent mycobacterial persistence in the absence of clinical manifestations. In a proportion of latently infected individuals infection eventually reactivates and becomes contagious, seriously influencing epidemiological situation. Mechanisms of Mycobacterium tuberculosis transition to dormancy and TB reactivation are poorly ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 14 شماره
صفحات -
تاریخ انتشار 2014